细胞膜中的蛋白质参与多种重要的细胞过程，包括信号转导、分子运输和细胞间通讯。它们对人类健康和疾病的重要性使其成为极具吸引力的治疗干预靶点。
Membrane proteins are critical in translational medicine.They facilitate essential processes like signaling and molecular transport. Their important role makes them prime therapeutic targets.
Get Started膜蛋白需要特定的脂质环境；对宿主细胞的潜在毒性，限制了产量；蛋白质在提取后的不稳定性；由于两亲性特征导致的纯化难度；以及许多膜蛋白在天然组织中含量低，需要使用重组表达系统。
Obtaining functional membrane proteins for structural and functional studies presents significant challenges:
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Require specific lipid environments for proper folding and function.
Overexpression can be toxic to host cells, limiting yield and viability.
Extracted membrane proteins tend to be unstable and prone to aggregation.
The amphipathic nature makes them difficult to purify while maintaining function.
Recombinant expression systems are essential for high protein yields.
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